469. Wax B. et al.: Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men. Journal of the International Society of Sports Nutrition 2012, 9(1):17.
470. Greer B.K., Jones B.T.: Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training. Journal of strength and conditioning research / National Strength & Conditioning Association 2011, 25(7):1789–94.
471. Karsegard V.L. et al.: L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. Nutrition 2004, 20(6):515–20.
472. Young C. et al.: Hemorrhagic stroke in young healthy male following use of sports supplement Jack3d. Military medicine 2012, 177(12):1450–4.
473. Prosser J.M. et al.: Adverse effects associated with arginine alpha-ketoglutarate containing supplements. Human & experimental toxicology 2009, 28(5):259–62.
474. Randhawa S. et al.: Anterior segment complications of a nutritional supplement. Journal of cataract and refractive surgery 2007, 33(5):918–20.
475. Chen W. et al.: Anthocyanin-rich purple wheat prolongs the life span of Caenorhabditis elegans probably by activating the DAF-16/FOXO transcription factor. J Agric Food Chem 2013, 61(12):3047–53.
476. Leenders M. et al.: Fruit and vegetable intake and causespecific mortality in the EPIC study. Eur J Epidemiol 2014, 29(9):639–52.
477. Pierpaoli W., Regelson W.: Pineal control of aging: effect of melatonin and pineal grafting on aging mice. Proc Natl Acad Sci USA 1994, 91(2):787–91.
478. Anisimov V.N. et al.: Melatonin as antioxidant, geroprotector and anticarcinogen. Biochim Biophys Acta 2006, 1757(5–6): 573–89.
479. Bubenik G.A., Konturek S.J.: Melatonin and aging: prospects for human treatment. J Physiol Pharmacol 2011, 62(1):13–9.
480. Ayyadevara S. et al.: Remarkable longevity and stress resistance of nematode PI3K-null mutants. Aging Cell 2008, 7(1):13–22.
481. Bernardes de Jesus B. et al.: Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO Mol Med 2012, 4(8):691–704.
482. Bivalacqua T.J. et al.: Gene transfer of extracellular SOD to the penis reduces O2-* and improves erectile function in aged rats. Am J Physiol Heart Circ Physiol 2003, 284(4):H1408–21.
483. Fayad R. et al.: Oral administration with papillomavirus pseudovirus encoding IL-2 fully restores mucosal and systemic immune responses to vaccinations in aged mice. J Immunol 2004, 173(4):2692–8.
484. Mouravlev A. et al.: Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats. Proc Natl Acad Sci USA 2006, 103(12):4705–10.
485. Nishida F. et al.: Restorative effect of intracerebroventricular insulin-like growth factor-I gene therapy on motor performance in aging rats. Neuroscience 2011, 177:195–206.
486. Schmidt U. et al.: In vivo gene transfer of parvalbumin improves diastolic function in aged rat hearts. Cardiovasc Res 2005, 66(2):318–23.
487. Wang H. et al.: Delayed angiogenesis in aging rats and therapeutic effect of adenoviral gene transfer of VEGF. Int J Mol Med 2004, 13(4):581–7.
488. Zhang G. et al.: Hypothalamic programming of systemic ageing involving IKK-beta, NF-kappaB and GnRH. Nature 2013,
497(7448):211–6.
489. Shen J. et al.: Transplantation of mesenchymal stem cells from young donors delays aging in mice. Sci Rep 2011, 1:67.
490. Villeda S.A. et al.: Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nat Med 2014, 20(6):659–63.
491. Liang P. et al.: Human neural stem cells promote corticospinal axons regeneration and synapse reformation in injured spinal cord of rats. Chin Med J (Engl) 2006, 119(16):1331–8.
492. Barberi T. et al.: Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 2003, 21(10):1200–7.
493. Petit G.H. et al.: The future of cell therapies and brain repair: Parkinson’s disease leads the way. Neuropathol Appl Neurobiol 2014, 40(1):60–70.
494. D’Amour K.A. et al.: Production of pancreatic hormoneexpressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006, 24(11):1392–401.
495. Johannesson B. et al.: Toward beta cell replacement for diabetes. EMBO J 2015, 34(7):841–55.
496. Takahashi K., Yamanaka S.: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126(4):663–76.
497. Zhong X.Y. et al.: Umbilical cord blood stem cells: what to expect. Ann NY Acad Sci 2010, 1205:17–22.
498. Xiao N. et al.: Co-transplantation of mesenchymal stromal cells and cord blood cells in treatment of diabetes. Cytotherapy 2013, 15(11):1374–84.
499. Wang D. et al.: Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience. Cell Transplant 2013, 22(12):2267–77.
500. Liu J. et al.: Clinical analysis of the treatment of spinal cord injury with umbilical cord mesenchymal stem cells. Cytotherapy 2013, 15(2):185–91.
501. Canavero S.: The “Gemini” spinal cord fusion protocol: Reloaded. Surg Neurol Int 2015, 6:18.
502. Behringer W. et al.: Survival without brain damage after clinical death of 60–120 mins in dogs using suspended animation by profound hypothermia. Crit Care Med 2003, 31(5):1523–31.
503. Balaban E.: Brain switching: studying evolutionary behavioral changes in the context of individual brain development. Int J Dev Biol 2005, 49(2–3):117–24.
504. Estrada V. et al.: Long-lasting significant functional improvement in chronic severe spinal cord injury following scar resection and polyethylene glycol implantation. Neurobiol Dis 2014, 67:165–79.
505. Breidenbach W.C. et al.: Outcomes of the first 2 American hand transplants at 8 and 6 years posttransplant. J Hand Surg Am 2008, 33(7):1039–47.
506. Minev I.R. et al.: Biomaterials. Electronic dura mater for longterm multimodal neural interfaces. Science 2015, 347(6218):159–63.
507. Soekadar S.R. et al.: An EEG/EOG-based hybrid brain-neural computer interaction (BNCI) system to control an exoskeleton for the paralyzed hand. Biomed Tech (Berl) 2015, 60(3):199–205.
508. Shih J.J. et al.: Brain-computer interfaces in medicine. Mayo Clin Proc 2012, 87(3):268–79.
509. Wissner-Gross A.D., Freer C.E.: Causal entropic forces. Phys Rev Lett 2013, 110(16):168702.
510. Pietschnig J., Voracek M.: One Century of Global IQ Gains: A Formal Meta-Analysis of the Flynn Effect (1909–2013). Perspect Psychol Sci 2015, 10(3):282–306.mm
511. Prescott V.E. et al: Transgenic expression of bean alpha-amylase inhibitor in peas results in altered structure and immunogenicity. J Agric Food Chem 2005,53(23):9023–30.
512. Genetically modified mush. Nat Biotechnol 2006, 24(1):2.
513. Lee R.Y. et al: Genetically modified alpha-amylase inhibitor peas are not specifically allergenic in mice. PLOS ONE 2013, 8(1):e52972.
514. Campbell P.M. et al: Comparison of the alpha-amylase inhibitor-1 from common bean (Phaseolus vulgaris) varieties and transgenic expression in other legumes – post-translational modifications and immunogenicity. J Agric Food Chem 2011, 59(11): 6047–54.
